William Schwindinger, assistant professor

Education

MD Albert Einstein College of Medicine

PhD Albert Einstein College of Medicine, Biochemistry

Teaching

Anatomy and Physiology laboratories, Molecular Biology, Pharmacology for the Health Sciences

Research Interests

My research interest is in G-protein coupled signal transduction. G-proteins initiate the cellular response to activation of cell surface receptors for numerous signals including hormones, neurotransmitters, paracrine factors, odorants, and light. G-proteins are composed of three subunits, an-subunit and a -dimer; each of these subunits is encoded by a gene family. My aim is discover the specific roles of individual G-protein -subunits in signal transduction, and how epigenetic regulation of their expression may be involved in human disease.

Mentored Student Presentations

• Bogdanowitz, A. and Schwindinger, W., Calcium Signaling in SH-SY5Y Cells and G Protein Subunit Gamma 4, COST Informal Poster Session, December 9. 2016.
• King, A., Evaluating G-Protein Subunit Gamma-4’s Effect on Cell Migration in a Model System of Kallmann Syndrome Using CRISPR/Cas9, Thesis Research Presentation and Defense, December 5, 2016.
• Place, J.-N. and Schwindinger, W., Methylation of GNG7 in Human Breast Cancer Tissues, Biennial Beta Beta Beta National Convention, Bethel University, St. Paul, MN, May 30 – June 5, 2016
• Young, J. and Schwindinger, W., Measuring Methylation of GNG11 in Human Breast Cancer, Beta Beta Beta National Biological Honor Society, Northeast District 2 Convention, Ursinus College, March 19, 2016

Grants

• PASSHE, Faculty Professional Development Annual Grant, May 2015- Oct. 2016, $9000
• Bloomsburg University, Research and Scholarship Mini-Grant, May 2016 May 2017, $5000

Service Activites

• Institutional Review Board for Human Subjects Research
• BAHS Faculty Search and Screen Sub-committee
• COST Faculty Support Work Group
• COST Curriculum Committee