IBC: Frequently Asked Questions

IBC: Frequently Asked Questions

What are the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules?

The NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines) detail procedures and practices fro the containment and safe conduct of various forms of research involving recombinant and synthetic nucleic acid molecules, including research involving genetically modified plants and animals, and human gene transfer research.

Who must comply with the NIH Guidelines?

All institutions that receive NIH funding for research involving recombinant or synthetic nucleic acid molecules must comply with the NIH Guidelines. Researchers at institutions that are subject to the NIH Guidelines must comply with the requirements even if their own project are not funded by NIH.

What is an Institutional Biosafety Committee?

Institutional Biosafety Committees (IBCs) provide local review and oversight of nearly all forms of research utilizing recombinant or synthetic nucleic acid molecules. They ensure that recombinant and synthetic nucleic acid research conducted at or sponsored by the institution is in compliance with the NIH Guidelines.

What is the NIH Office of Biotechnology Activities?

The NIH Office of Biotechnology Activities (OBA) promotes science, safety, and ethics in biotechnology through the advancement of knowledge, enhancement of public understanding, and development of sound public policies. A core responsibility of OBA is to foster awareness of, and adherence to, the standards and practices set forth in the NIH Guidelines.